Study trend Italian Multiple Sclerosis Register (data at 28th Nov 2025)
TOTAL PATIENTS: 97.015
Distribution by age classes (age at 28th Nov 2025)
Symptoms at the onset
| Symptom |
% Patient |
| Supratentorial |
19.43% |
| Optic |
19.52% |
| Spinal |
23.01% |
| Brainstem |
17.63% |
| Polysymptomatic |
11.21% |
| Other |
9.2% |
Distribution for symptoms at onset
First MS-Course
| MS-Course |
% Patient |
| CIS |
86.93% |
| PP MS |
5.53% |
| Missing |
7.54% |
CIS=Clinically Isolated Syndrome;
PP MS=Primary Progressive;
RR MS=Relapsing Remitting
Distribution First MS-Course
Last MS-Course
| MS-Course |
% Pazienti |
| RR MS |
71.73% |
| SP MS |
10.65% |
| CIS |
4.55% |
| PP MS |
3.57% |
| PR MS |
1.96% |
| Missing |
7.54% |
RR MS=Relapsing Remitting;
SP MS=Secondary Progressive;
CIS=Clinically Isolated Syndrome;
PP MS=Primary Progressive;
PR MS=Progressive Relapsing;
Distribution Last MS-Course
Classes of sex/age at onset
| Age class |
% Male |
% Female |
| 0-17 yy |
2.04% |
4.48% |
| 18-24 yy |
6.57% |
13.73% |
| 25-32 yy |
9.07% |
18.21% |
| 33-40 yy |
6.67% |
13.62% |
| 41-48 yy |
4.44% |
9.71% |
| 49-56 yy |
2.33% |
4.52% |
| 57-64 yy |
0.82% |
1.32% |
| >=65 yy |
0.22% |
0.36% |
| Missing data |
1.89% |
Distribution of sex/age at onset
