Study trend Italian Multiple Sclerosis Register (data at 30th Jan 2026)
TOTAL PATIENTS: 97.770
Distribution by age classes (age at 30th Jan 2026)
Symptoms at the onset
| Symptom |
% Patient |
| Supratentorial |
19.58% |
| Optic |
19.65% |
| Spinal |
23.27% |
| Brainstem |
17.8% |
| Polysymptomatic |
11.3% |
| Other |
8.4% |
Distribution for symptoms at onset
First MS-Course
| MS-Course |
% Patient |
| CIS |
87.92% |
| PP MS |
5.6% |
| Missing |
6.48% |
CIS=Clinically Isolated Syndrome;
PP MS=Primary Progressive;
RR MS=Relapsing Remitting
Distribution First MS-Course
Last MS-Course
| MS-Course |
% Pazienti |
| RR MS |
72.62% |
| SP MS |
10.74% |
| CIS |
4.56% |
| PP MS |
3.62% |
| PR MS |
1.97% |
| Missing |
6.51% |
RR MS=Relapsing Remitting;
SP MS=Secondary Progressive;
CIS=Clinically Isolated Syndrome;
PP MS=Primary Progressive;
PR MS=Progressive Relapsing;
Distribution Last MS-Course
Classes of sex/age at onset
| Age class |
% Male |
% Female |
| 0-17 yy |
2.01% |
4.45% |
| 18-24 yy |
6.61% |
13.78% |
| 25-32 yy |
9.13% |
18.22% |
| 33-40 yy |
6.69% |
13.66% |
| 41-48 yy |
4.47% |
9.66% |
| 49-56 yy |
2.32% |
4.48% |
| 57-64 yy |
0.82% |
1.27% |
| >=65 yy |
0.21% |
0.33% |
| Missing data |
1.89% |
Distribution of sex/age at onset
