Study trend Italian Multiple Sclerosis Register (data at 31th Jul 2025)
TOTAL PATIENTS: 95.294
Distribution by age classes (age at 31th Jul 2025)
Symptoms at the onset
| Symptom |
% Patient |
| Supratentorial |
19.53% |
| Optic |
19.52% |
| Spinal |
22.98% |
| Brainstem |
17.68% |
| Polysymptomatic |
11.2% |
| Other |
9.09% |
Distribution for symptoms at onset
First MS-Course
| MS-Course |
% Patient |
| CIS |
86.9% |
| PP MS |
5.49% |
| Missing |
7.61% |
CIS=Clinically Isolated Syndrome;
PP MS=Primary Progressive;
RR MS=Relapsing Remitting
Distribution First MS-Course
Last MS-Course
| MS-Course |
% Pazienti |
| RR MS |
71.65% |
| SP MS |
10.7% |
| CIS |
4.54% |
| PP MS |
3.52% |
| PR MS |
1.96% |
| Missing |
7.63% |
RR MS=Relapsing Remitting;
SP MS=Secondary Progressive;
CIS=Clinically Isolated Syndrome;
PP MS=Primary Progressive;
PR MS=Progressive Relapsing;
Distribution Last MS-Course
Classes of sex/age at onset
| Age class |
% Male |
% Female |
| 0-17 yy |
2.04% |
4.5% |
| 18-24 yy |
6.6% |
13.75% |
| 25-32 yy |
9.08% |
18.24% |
| 33-40 yy |
6.64% |
13.63% |
| 41-48 yy |
4.42% |
9.68% |
| 49-56 yy |
2.32% |
4.49% |
| 57-64 yy |
0.8% |
1.3% |
| >=65 yy |
0.22% |
0.35% |
| Missing data |
1.94% |
Distribution of sex/age at onset
